- Project Hope for the Homeless
- Lake Humane Society
- Downs Designs Dreams
- 24 in 24 Challenge for A Special Wish Cleveland
- Back to school theme - school supply drive to benefit schools in Lake, Geauga, Cuyahoga, and Ashtabula counties.
- Hunger theme - participants donated or volunteered time for a local charity of their choice.
- Mental health awareness theme
- Random Acts of Kindness month - 'fee' to participate was performing a random act of kindness
- WomenSafe
- Ronald McDonald House
- Big Brothers Big Sisters of NE Ohio
- Animal shelters
- Cancer charity theme
- Dance Does It - helped a local dance group fund their dream of participating in Special Olympics in Austria
- Girls with Sole (empowering at-risk teen girls through fitness)
- Sub Zero Mission (helping homeless stay warm)
- Project Outrun (empowering kids with cancer through running shoes)
- Environmental theme - participants 'plogged' (picked up litter while on a group jog) and some donated to Chagrin River Watershed
- Team Red White and Blue
- RunningDog
- Youth development programs
- Wigs for Kids
- Running2BWell